ALKBH2 anticorps

N° du produit ABIN2422380

Détail du produit anti-ALKBH2 anticorps

Antigène: ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALKBH2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogène: Recombinant protein of human ALKBH2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ALKBH2

Antigène: ALKBH2 (AlkB, Alkylation Repair Homolog 2 (ALKBH2))

Autre désignation: ALKBH2 (ALKBH2 Produits)

Synonymes: anticorps si:dkey-65b12.2, anticorps ABH2, anticorps 9530023G02, anticorps AU016977, anticorps Abh2, anticorps mABH2, anticorps RGD1306377, anticorps alkB homolog 2, alpha-ketoglutarate dependent dioxygenase, anticorps alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase, anticorps ALKBH2, anticorps alkbh2, anticorps Alkbh2

Sujet: The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

Poids moléculaire: Calculated MW: 29 kDa

Pathways: Réparation de l'ADN