NFASC anticorps

N° du produit ABIN2426284

Détail du produit anti-NFASC anticorps

Antigène: NFASC (Neurofascin (NFASC))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFASC est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human NFASC

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C/-80 °C

Stockage commentaire: Store at -20°C (regular) and -80°C (long term).

Détails sur NFASC

Antigène: NFASC (Neurofascin (NFASC))

Autre désignation: NFASC (NFASC Produits)

Synonymes: anticorps sc:d0205, anticorps NF, anticorps NRCAML, anticorps AA387016, anticorps D430023G06Rik, anticorps mKIAA0756, anticorps neurofascin, anticorps neurofascin homolog (chicken) a, anticorps NFASC, anticorps nfasca, anticorps Nfasc

Sujet: This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.
Synonyms: NF, NRCAML

Pathways: Cell-Cell Junction Organization