LRRC8A anticorps

N° du produit ABIN2459288

Détail du produit anti-LRRC8A anticorps

Antigène: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC8A est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LRRC8A.

Information d'application

Indications d'application: LRRC8A antibody can be used for detection of LRRC8A by ELISA at 1:62500. LRRC8A antibody can be used for detection of LRRC8A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store LRRC8A antibody at -20 °C.

Détails sur LRRC8A

Antigène: LRRC8A (Leucine Rich Repeat Containing 8 Family, Member A (LRRC8A))

Autre désignation: LRRC8A (LRRC8A Produits)

Synonymes: anticorps AGM5, anticorps LRRC8, anticorps Lrrc8, anticorps mKIAA1437, anticorps wu:fb18g12, anticorps wu:fi21b10, anticorps LLRC8A, anticorps leucine rich repeat containing 8 VRAC subunit A, anticorps leucine rich repeat containing 8A, anticorps leucine rich repeat containing 8 VRAC subunit Aa, anticorps leucine-rich repeat containing 8 family member A S homeolog, anticorps leucine rich repeat containing 8 family member A, anticorps LRRC8A, anticorps Lrrc8a, anticorps lrrc8aa, anticorps lrrc8a.S

Sujet: LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Poids moléculaire: 94 kDa

ID gène: 56262

NCBI Accession: NP_062540

UniProt: Q8IWT6