MAP2K7 anticorps (pThr275)

N° du produit ABIN2568342

Détail du produit anti-MAP2K7 anticorps

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Épitope: pThr275

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K7 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous levels of MAP2K7 only when phosphorylated at threonine 275.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: MAP2K7 (phospho Thr275) antibody was raised against a peptide sequence around phosphorylation site of threonine 275 (A-K-T (p)-R-S) derived from Human MAP2K7.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur MAP2K7

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Autre désignation: MAP2K7 (MAP2K7 Produits)

Synonymes: anticorps MAP2K7, anticorps 2, anticorps JNKK, anticorps Jnkk2, anticorps Mapkk7, anticorps Mek7, anticorps Mkk7, anticorps MAPKK7, anticorps MKK7, anticorps PRKMK7, anticorps SAPKK-4, anticorps SAPKK4, anticorps 5930412N11Rik, anticorps JNKK 2, anticorps MAPKK 7, anticorps MEK 7, anticorps Prkmk7, anticorps sek2, anticorps si:ch211-254d18.2, anticorps map2k7-A, anticorps mitogen-activated protein kinase kinase 7, anticorps mitogen activated protein kinase kinase 7, anticorps mitogen-activated protein kinase kinase 7 L homeolog, anticorps MAP2K7, anticorps Map2k7, anticorps map2k7, anticorps map2k7.L

Sujet: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.

Poids moléculaire: 43 kDa

ID gène: 5609

NCBI Accession: NP_660186

UniProt: O14733

Pathways: Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling