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P2RX7 anticorps
P2RX7
Reactivité: Souris
FACS
Hôte: Rat
Monoclonal
1F11
unconjugated
N° du produit ABIN2665313
Détail du produit anti-P2RX7 anticorps
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Antigène
Voir toutes P2RX7 Anticorps
P2RX7
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
Reactivité
Toutes les réactivités sur P2RX7 Anticorps
Souris
Hôte
Toutes les hôtes sur P2RX7 Anticorps
Rat
Clonalité
Toutes les clonalités sur P2RX7 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers P2RX7 Anticorps
Cet anticorp P2RX7 est non-conjugé
Application
Tous les applications à travers P2RX7 Anticorps.
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
1F11
Isotype
IgG2b kappa
Top Product
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Alternatives
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anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibody
P2RX7
Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye
WB, IHC
Hôte: Lapin
Polyclonal
unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 136-152), (Extracellular Loop) antibody
P2RX7
Reactivité: Humain, Souris, Rat
WB, IHC, FACS, IF, ICC, LCI
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
(cache)
Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur P2RX7
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Antigène
P2RX7
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
Autre désignation
P2X7R (P2RX7 Produits )
Synonymes
anticorps p2xr7, anticorps P2RX7, anticorps P2X7, anticorps AI467586, anticorps P2X(7), anticorps P2X7R, anticorps p2x7, anticorps purinergic receptor P2X 7, anticorps purinergic receptor P2X, ligand-gated ion channel, 7, anticorps P2X purinoceptor 7, anticorps P2RX7, anticorps p2rx7, anticorps LOC100458463, anticorps P2rx7
Sujet
P2X7R, also known as P2X7 receptor, belongs to the family of ligand-gated ion channel receptors. It is expressed on T cells, B cells, macrophages, and microglia. The receptor opens in the presence of extracellular ATP or NAD, leading to intracellular calcium mobilization. P2X7R activation requires higher concentrations of ATP compared to other P2X receptors. Longer stimulation results in larger pores, allowing passage of larger molecules. Activation of these molecules also leads to mitochondrial and cytoskeletal changes as well as IL-1β maturation and release. Ligation of P2X7 receptor can lead to membrane blebbing and cell death.
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Synaptic Vesicle Exocytosis
Vus récemment
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