CD28 anticorps
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- Antigène Voir toutes CD28 Anticorps
- CD28
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD28 est non-conjugé
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Application
- Flow Cytometry (FACS)
- Marque
- Ultra-LEAF™
- Réactivité croisée
- Chimpanzé, Babouin, Cynomolgus, Macaque rhésus, Pigtailed Macaque, Capuchin Monkey, Sooty mangabey (Cercocebus atys), Squirrel Monkey (Saimiri spec.)
- Purification
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- Clone
- CD28-2
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD28 Anticorps primaire
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anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reactivité: Humain, Souris, Rat FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Hôte: Lapin Polyclonal unconjugated
anti-CD28 (CD28) antibodyCD28 Reactivité: Humain, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Hôte: Souris Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) antibody (FITC)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 FITC
anti-CD28 (CD28) (AA 19-152) antibodyCD28 Reactivité: Humain FACS, ELISA Hôte: Lapin Monoclonal DM61 unconjugated Recombinant Antibody
anti-CD28 (CD28) antibodyCD28 Reactivité: Humain, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Hôte: Souris Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) antibodyCD28 Reactivité: Rat FACS, IP Hôte: Souris Monoclonal JJ319 unconjugated
anti-CD28 (CD28) antibody (PE)CD28 Reactivité: Rat FACS Hôte: Souris Monoclonal JJ319 PE
anti-CD28 (CD28) antibody (APC)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 APC
anti-CD28 (CD28) antibody (PE)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 PE
anti-CD28 (CD28) antibody (PerCP)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 PerCP
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Agent conservateur
- Azide free
- Conseil sur la manipulation
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- CD28
- Autre désignation
- CD28 (CD28 Produits)
- Synonymes
- anticorps Tp44, anticorps CD28RNA, anticorps cd28, anticorps CD28 molecule, anticorps CD28 antigen, anticorps Cd28 molecule, anticorps CD28 molecule L homeolog, anticorps CD28, anticorps Cd28, anticorps cd28.L
- Sujet
- CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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