NFKBIA anticorps

N° du produit ABIN2668610

Détail du produit anti-NFKBIA anticorps

Antigène: NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NFKBIA est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity Purified

Immunogène: This antibody was raised against a synthetic peptide containing phosphorylated serines at amino acid residue(s) 32 and 36 of human Phosphorylated-IkBa.

Clone: 39A1431

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 μg/μL

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -80 °C

Stockage commentaire: Antibodies in solution can be stored at -80 °C for 2 years.

Date de péremption: 6 months

Références pour anticorps anti-NFKBIA (ABIN2668610)

Cao, Morin, Sengers, Metz, Roger, Maheux, Akoum: "Tumour necrosis factor-alpha up-regulates macrophage migration inhibitory factor expression in endometrial stromal cells via the nuclear transcription factor NF-kappaB." dans: Human reproduction (Oxford, England), Vol. 21, Issue 2, pp. 421-8, (2006) (PubMed).

Cao, Morin, Metz, Maheux, Akoum: "Stimulation of macrophage migration inhibitory factor expression in endometrial stromal cells by interleukin 1, beta involving the nuclear transcription factor NFkappaB." dans: Biology of reproduction, Vol. 73, Issue 3, pp. 565-70, (2005) (PubMed).

Han, Karabiyikoglu, Kelly, Sobel, Yenari: "Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke." dans: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 23, Issue 5, pp. 589-98, (2003) (PubMed).

Détails sur NFKBIA

Antigène: NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))

Autre désignation: IkappaBalpha (NFKBIA Produits)

Synonymes: anticorps IKBA, anticorps MAD-3, anticorps NFKBI, anticorps AI462015, anticorps Nfkbi, anticorps RL/IF-1, anticorps ECI-6/IKBA, anticorps NFKBIA, anticorps ikbaB, anticorps wu:fb81f08, anticorps zgc:56666, anticorps zgc:77616, anticorps ikbaA, anticorps wu:fj16a07, anticorps zgc:85769, anticorps NFKB inhibitor alpha, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a, anticorps NFKBIA, anticorps Nfkbia, anticorps nfkbiab, anticorps nfkbiaa

Sujet: IκBα phospho Ser32,36 - NFκB (NFκB p50 and NFκB p65) signaling is controlled to a large extent by the sequestration of the NFκB complex in the cytoplasm by its association with one of the IκB family of proteins. IκBα is phosphorylated at Ser32 and Ser36 by the IκB Kinase (IKK) complex, resulting in the degradation of IκB and the nuclear translocation of NFκB.

Poids moléculaire: 40 kDa

ID gène: 4792

Pathways: Signalisation NF-kappaB, TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling