Cet anticorp Integrin beta 2 est conjugé à/à la Biotin
Application
Flow Cytometry (FACS)
Marque
BD Pharmingen™
Attributs du produit
The C71/16 antibody reacts with the common β2 chain of LFA-1 (CD11a/CD18, αLβ2 integrin), Mac-1 (CD11b/CD18, αMβ2 integrin), and gp150, 95 (CD11c/CD18, αxβ2 integrin). Expression of CD18 is limited to leukocytes, where it is widely distributed in consort with the three integrin α chains (CD11a, CD11b, and CD11c). Among splenocytes, NK cells have the highest density of CD18, and T lymphocytes express a higher density than the remaining cells. The β2 integrins are important mediators of leukocyte-endothelium interactions.
BD Pharmingen™ Biotin Rat Anti-Mouse CD18 - Biotin - Clone C71/16 - Isotype Rat IgG2a, κ - Reactivity Ms - 0.1 mg
Purification
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogène
Cell membrane glycoproteins from mouse T-cell lymphoma BW5147
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
Stock
4 °C
Stockage commentaire
Store undiluted at 4°C.
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Springer: "Adhesion receptors of the immune system." dans: Nature, Vol. 346, Issue 6283, pp. 425-34, (1990) (PubMed).
Trowbridge, Omary: "Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1." dans: The Journal of experimental medicine, Vol. 154, Issue 5, pp. 1517-24, (1982) (PubMed).