CD47 anticorps
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- Antigène Voir toutes CD47 Anticorps
- CD47
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD47 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Marque
- BD Pharmingen™
- Attributs du produit
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Reacts with a 42-52 kD N-linked glycan protein. CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD47 - Purified - Clone B6H12 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg - Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Clone
- B6H12
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD47 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store undiluted at 4°C.
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Rh-related antigen CD47 is the signal-transducer integrin-associated protein." dans: The Journal of biological chemistry, Vol. 269, Issue 3, pp. 1567-70, (1994) (PubMed).
: "A novel member of the integrin receptor family mediates Arg-Gly-Asp-stimulated neutrophil phagocytosis." dans: The Journal of cell biology, Vol. 108, Issue 5, pp. 1935-43, (1989) (PubMed).
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Rh-related antigen CD47 is the signal-transducer integrin-associated protein." dans: The Journal of biological chemistry, Vol. 269, Issue 3, pp. 1567-70, (1994) (PubMed).
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- Antigène
- CD47
- Autre désignation
- CD47 (CD47 Produits)
- Synonymes
- anticorps IAP, anticorps MER6, anticorps OA3, anticorps 9130415E20Rik, anticorps AA407862, anticorps AI848868, anticorps AW108519, anticorps B430305P08Rik, anticorps Itgp, anticorps CD47/IAP, anticorps alkaline phosphatase, intestinal, anticorps CD47 molecule, anticorps CD47 antigen (Rh-related antigen, integrin-associated signal transducer), anticorps Cd47 molecule, anticorps ALPI, anticorps CD47, anticorps Cd47
- Sujet
- Synonyms: IAP
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