NFATC3 anticorps

N° du produit ABIN272044

Détail du produit anti-NFATC3 anticorps

Antigène: NFATC3 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFATC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of NFAT4 protein. (region surrounding Glu159)

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/10000approx. 1/20000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NFATC3

Antigène: NFATC3 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3))

Autre désignation: NFAT4 / NFATC3 (NFATC3 Produits)

Synonymes: anticorps NFATC3, anticorps NFATx, anticorps nf-at, anticorps nfat4, anticorps nfatx, anticorps C80703, anticorps D8Ertd281e, anticorps NFAT4, anticorps NFATX, anticorps nuclear factor of activated T-cells 3, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3, anticorps nuclear factor of activated T-cells 3 S homeolog, anticorps NFATC3, anticorps nfatc3, anticorps Nfatc3, anticorps nfatc3.S

Sujet: NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurindependent 4) is a member of the nuclear factors of activated T cells DNAbinding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components, a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.Synonyms: NF-ATc3, NFATc3, Nuclear factor of activated T-cells, T-cell transcription factor NFAT4, T-cell transcription factor NFAT4, cytoplasmic 3

Poids moléculaire: approx. 115 kDa

ID gène: 4775

NCBI Accession: NP_004546

UniProt: Q12968

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Chromatin Binding