PKC epsilon anticorps

N° du produit ABIN2729610

Détail du produit anti-PKC epsilon anticorps

Antigène: PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PKC epsilon est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Attributs du produit: Homo sapiens protein kinase C, epsilon (PRKCE)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human PRKCE (NP_005391) produced in HEK293T cell.

Clone: 4G8

Isotype: IgG2b

Information d'application

Indications d'application: WB 1:1000~2000, IHC 1:150, IF 1:100, FLOW 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PKC epsilon

Antigène: PKC epsilon (PRKCE) (Protein Kinase C, epsilon (PRKCE))

Autre désignation: PRKCE (PRKCE Produits)

Synonymes: anticorps PKCE, anticorps nPKC-epsilon, anticorps 5830406C15Rik, anticorps PKC[e], anticorps PKCepsilon, anticorps Pkce, anticorps R75156, anticorps fj59b07, anticorps prkce, anticorps wu:fj59b07, anticorps pkce, anticorps pkc-epsilon, anticorps PRKCH, anticorps protein kinase C epsilon, anticorps protein kinase C, epsilon, anticorps protein kinase C, epsilon a, anticorps PRKCE, anticorps Prkce, anticorps prkcea, anticorps prkce

Sujet: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.

Poids moléculaire: 83.5 kDa

ID gène: 5581

NCBI Accession: NM_005400

HGNC: 5581

Pathways: TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling