SERPINB5 anticorps (Middle Region)
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- Antigène Voir toutes SERPINB5 Anticorps
- SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Chien, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SERPINB5 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 93%, Mouse: 86%, Rabbit: 86%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against SERPINB5. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SERPINB5
- Top Product
- Discover our top product SERPINB5 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 375 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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SERPINB5 Promoter Hypomethylation Differentiates Pancreatic Ductal Adenocarcinoma From Pancreatitis." dans: Pancreas, Vol. 45, Issue 5, pp. 743-7, (2016) (PubMed).
: "Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy." dans: Journal of proteome research, Vol. 12, Issue 1, pp. 455-69, (2013) (PubMed).
: "SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma." dans: BMC cancer, Vol. 10, pp. 549, (2010) (PubMed).
: "
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SERPINB5 Promoter Hypomethylation Differentiates Pancreatic Ductal Adenocarcinoma From Pancreatitis." dans: Pancreas, Vol. 45, Issue 5, pp. 743-7, (2016) (PubMed).
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- Antigène
- SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
- Autre désignation
- SERPINB5 (SERPINB5 Produits)
- Synonymes
- anticorps 1110036M19Rik, anticorps AI462524, anticorps AI646751, anticorps Maspin, anticorps PI-5, anticorps Spi7, anticorps ovalbumin, anticorps PI5, anticorps maspin, anticorps Pi5, anticorps serine (or cysteine) peptidase inhibitor, clade B, member 5, anticorps serpin family B member 5, anticorps serpin peptidase inhibitor, clade B (ovalbumin), member 5 S homeolog, anticorps Serpinb5, anticorps SERPINB5, anticorps serpinb5.S
- Sujet
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As a tumor suppressor, it blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Alias Symbols: PI5, maspin
Protein Interaction Partner: SUMO2, WWOX, FBXO32, KHDRBS3, ISG15, UBC, Cdk1, UCHL5, HDAC1,
Protein Size: 375 - Poids moléculaire
- 41 kDa
- ID gène
- 5268
- NCBI Accession
- NM_002639, NP_002630
- UniProt
- P36952
- Pathways
- Signalisation p53
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