WNT5A anticorps (Middle Region)
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- Antigène Voir toutes WNT5A Anticorps
- WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WNT5A est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- GGCGDNIDYG YRFAKEFVDA RERERIHAKG SYESARILMN LHNNEAGRRT
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 87%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 80%
- Attributs du produit
- This is a rabbit polyclonal antibody against WNT5A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human WNT5A
- Top Product
- Discover our top product WNT5A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 380 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))
- Autre désignation
- WNT5A (WNT5A Produits)
- Synonymes
- anticorps hWNT5A, anticorps wnt-5A, anticorps wnt5a-B, anticorps WNT5A, anticorps 8030457G12Rik, anticorps Wnt-5a, anticorps Wnt family member 5A, anticorps Wnt family member 5A S homeolog, anticorps wingless-type MMTV integration site family, member 5a, anticorps wingless-type MMTV integration site family, member 5A, anticorps wingless-related MMTV integration site 5A, anticorps Wnt signaling ligand, anticorps WNT5A, anticorps Wnt5a, anticorps wnt5a.S, anticorps wnt5a, anticorps LOC578814, anticorps wnt5
- Sujet
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT5A is a member of the WNT protein family. It shows 98 % , 98 % and 87 % amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 %, 98 % and 87 % amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: hWNT5A
Protein Interaction Partner: UBC, LRP6, FZD2, FZD1, ROR2, FZD5,
Protein Size: 380 - Poids moléculaire
- 42 kDa
- ID gène
- 7474
- NCBI Accession
- NM_003392, NP_003383
- UniProt
- P41221
- Pathways
- Signalisation WNT, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size, Tube Formation
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