NR4A1 anticorps (Middle Region)
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- Antigène Voir toutes NR4A1 Anticorps
- NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NR4A1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- FQKCLAVGMV KEVVRTDSLK GRRGRLPSKP KQPPDASPAN LLTSLVRAHL
- Homologie
- Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against NR4A1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human NR4A1
- Top Product
- Discover our top product NR4A1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 598 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development." dans: Neuron, Vol. 91, Issue 6, pp. 1219-1227, (2016) (PubMed).
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Transformation of the Radial Glia Scaffold Demarcates Two Stages of Human Cerebral Cortex Development." dans: Neuron, Vol. 91, Issue 6, pp. 1219-1227, (2016) (PubMed).
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- Antigène
- NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
- Autre désignation
- NR4A1 (NR4A1 Produits)
- Synonymes
- anticorps GFRP1, anticorps HMR, anticorps N10, anticorps NAK-1, anticorps NGFIB, anticorps NP10, anticorps NUR77, anticorps TR3, anticorps NGFI-B, anticorps Gfrp, anticorps Hbr-1, anticorps Hbr1, anticorps Hmr, anticorps TIS1, anticorps nur77, anticorps Ngfi-b, anticorps Nur77, anticorps nuclear receptor subfamily 4 group A member 1, anticorps nuclear receptor subfamily 4, group A, member 1, anticorps NR4A1, anticorps Nr4a1
- Sujet
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NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alias Symbols: GFRP1, HMR, MGC9485, N10, NAK-1, NGFIB, NP10, NUR77, TR3
Protein Interaction Partner: KRTAP10-5, KRTAP10-1, LONRF1, PGBD1, BCL2L10, CDKN2D, BCL2A1, BCL2, TUBB4A, VASP, ANKIB1, CUTA, NFKB1, SMAD3, LSS, HADHA, GLUD1, GK, CPT1A, SERPING1, ABCC6, ABCC13, SOCS4, ABCG8, DIABLO, HCVgp1, ABCA5, CHEK2, SUGT1, PRDX4, PRDX6, CHD1L, ABCB11, ARHGEF5, U
Protein Size: 598 - Poids moléculaire
- 64 kDa
- ID gène
- 3164
- NCBI Accession
- NM_002135, NP_002126
- UniProt
- P22736
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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