PAK4 anticorps (Middle Region)
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- Antigène Voir toutes PAK4 Anticorps
- PAK4 (P21-Activated Kinase 4 (PAK4))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PAK4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- EPQLAPPACT PAAPAVPGPP GPRSPQREPQ RVSHEQFRAA LQLVVDPGDP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PAK4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of Human PAK4
- Top Product
- Discover our top product PAK4 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PAK4 (P21-Activated Kinase 4 (PAK4))
- Autre désignation
- PAK4 (PAK4 Produits)
- Synonymes
- anticorps 5730488L07Rik, anticorps AW555722, anticorps mKIAA1142, anticorps im:5916170, anticorps wu:fd12b01, anticorps zgc:92014, anticorps p21 (RAC1) activated kinase 4, anticorps p21 protein (Cdc42/Rac)-activated kinase 4, anticorps PAK4, anticorps Pak4, anticorps pak4
- Sujet
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PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: -
Protein Interaction Partner: SH3RF2, HECW2, UBC, LATS2, YWHAQ, YWHAB, SRPK2, SRPK1, FBXO25, YWHAE, APP, POT1, TERF1, YWHAZ, YWHAG, RAN, CDC42, GATAD2A, PAK4, LIMK1, ITGAV, FGFR2, ITGB5, DLST, GRB2, RAC1, LRRK1, SFN, SSH1,
Protein Size: 591 - Poids moléculaire
- 65 kDa
- ID gène
- 10298
- NCBI Accession
- NM_005884, NP_005875
- UniProt
- O96013
- Pathways
- Signalisation RTK
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