RALB anticorps (Middle Region)

N° du produit ABIN2786741

Détail du produit anti-RALB anticorps

Antigène: RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Chévre, Cobaye, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RALB est non-conjugé

Application: Western Blotting (WB)

Séquence: EHESFTATAE FREQILRVKS EEDKIPLLVV GNKSDLEERR QVPVDEARGK

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Ralb. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Mouse Ralb

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 206 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RALB

Antigène: RALB (Ralb) (V-Ral Simian Leukemia Viral Oncogene Homolog B (Ras Related, GTP Binding Protein) (Ralb))

Autre désignation: Ralb (Ralb Produits)

Synonymes: anticorps dRalb, anticorps 5730472O18Rik, anticorps Ral B, anticorps ralb, anticorps xralb, anticorps zgc:100801, anticorps KRAS2, anticorps k-ras, anticorps RAS like proto-oncogene B, anticorps v-ral simian leukemia viral oncogene B, anticorps v-ral simian leukemia viral oncogene homolog B L homeolog, anticorps v-ral simian leukemia viral oncogene homolog Ba (ras related), anticorps v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein), anticorps RALB, anticorps Ralb, anticorps ralb.L, anticorps ralba, anticorps ralb

Sujet: Ralb is a multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Ralb accomplishes its multiple functions by interacting with distinct downstream effectors. It acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. It is required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Ralb plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. It is required for suppression of apoptosis.
Alias Symbols: 5730472O18Rik
Protein Interaction Partner: Rgl3,
Protein Size: 206

Poids moléculaire: 23 kDa

ID gène: 64143

NCBI Accession: NM_022327, NP_071722

UniProt: Q9JIW9

Pathways: Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events