Melanophilin anticorps (C-Term)

N° du produit ABIN2788093

Détail du produit anti-Melanophilin anticorps

Antigène: Melanophilin (MLPH)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Melanophilin est non-conjugé

Application: Western Blotting (WB)

Séquence: NLPIFLPRVA GKLGKRPEDP NADPSSEAKA MAVPYLLRRK FSNSLKSQGK

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MLPH. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MLPH

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 600 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Melanophilin

Antigène: Melanophilin (MLPH)

Autre désignation: MLPH (MLPH Produits)

Synonymes: anticorps MGC155106, anticorps LOC100222096, anticorps 2210418F23Rik, anticorps 5031433I09Rik, anticorps AW228792, anticorps D1Wsu84e, anticorps Slac-2a, anticorps l(1)-3Rk, anticorps l1Rk3, anticorps ln, anticorps SLAC2-A, anticorps melanophilin, anticorps MLPH, anticorps mlph, anticorps Mlph

Sujet: This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: MGC2771, MGC59733, SLAC2-A
Protein Interaction Partner: CUL2, UBC, RAB27B, RAB27A, MYO5A, RAB10, RPH3A, ACTA1,
Protein Size: 600

Poids moléculaire: 66 kDa

ID gène: 79083

NCBI Accession: NM_024101, NP_077006

UniProt: Q9BV36