KLRC1 anticorps (C-Term)

N° du produit ABIN2788754

Détail du produit anti-KLRC1 anticorps

Antigène: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLRC1 est non-conjugé

Application: Western Blotting (WB)

Séquence: SHHPWVTMNG LAFKHEIKDS DNAELNCAVL QVNRLKSAQC GSSIIYHCKH

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KLRC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human KLRC1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 215 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KLRC1

Antigène: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Autre désignation: KLRC1 (KLRC1 Produits)

Synonymes: anticorps rNKG2A, anticorps NKG2-A, anticorps NKG2A, anticorps KLRC1, anticorps CD159A, anticorps NKG2, anticorps CD159a, anticorps NKG2B, anticorps killer cell lectin like receptor C1, anticorps NKG2-A/NKG2-B type II integral membrane protein-like, anticorps killer cell lectin-like receptor subfamily C, member 3, anticorps killer cell lectin-like receptor subfamily C, member 1, anticorps Klrc1, anticorps KLRC1, anticorps NKG2A, anticorps KLRC3

Sujet: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Alias Symbols: CD159A, MGC13374, MGC59791, NKG2, NKG2A
Protein Interaction Partner: PMP22, MAL, KLRD1, PTPN6, PTPN11, HLA-E,
Protein Size: 215

Poids moléculaire: 24 kDa

ID gène: 3821

NCBI Accession: NM_007328, NP_015567