SLC7A5 anticorps (N-Term)

N° du produit ABIN2789581

Détail du produit anti-SLC7A5 anticorps

Antigène: SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC7A5 est non-conjugé

Application: Western Blotting (WB)

Séquence: MAGAGPKRRA LAAPAAEEKE EAREKMLAAK SADGSAPAGE GEGVTLQRNI

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SLC7A5. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 507 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SLC7A5

Antigène: SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))

Autre désignation: SLC7A5 (SLC7A5 Produits)

Synonymes: anticorps 4F2LC, anticorps CD98, anticorps D16S469E, anticorps E16, anticorps LAT1, anticorps MPE16, anticorps hLAT1, anticorps D0H16S474E, anticorps TA1, anticorps JHI-21, anticorps SLC7A5, anticorps LAT-1, anticorps slc7a5a, anticorps 4F2, anticorps 4F2HC, anticorps AI314110, anticorps Cd98, anticorps Ly-10, anticorps Ly-m10, anticorps Ly10, anticorps Mdu1, anticorps Mgp-2hc, anticorps NACAE, anticorps solute carrier family 7 member 5, anticorps solute carrier family 7 (cationic amino acid transporter, y+ system), member 5, anticorps solute carrier family 7 (amino acid transporter light chain, L system), member 5, anticorps solute carrier family 7 member 5 S homeolog, anticorps solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2, anticorps SLC7A5, anticorps Slc7a5, anticorps slc7a5.S, anticorps Slc3a2

Sujet: SLC7A5 is a sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. SLC7A5 is involved in cellular amino acid uptake. SLC7A5 acts as an amino acid exchanger. SLC7A5 is involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. SLC7A5 plays a role in neuronal cell proliferation (neurogenesis) in brain. SLC7A5 is involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. SLC7A5 is involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. SLC7A5 may play an important role in high-grade gliomas. SLC7A5 mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. SLC7A5 acts as the major transporter of tyrosine in fibroblasts.
Alias Symbols: 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1
Protein Interaction Partner: UBC, SUMO2, LGR4, NOS2, HNRNPU, ELAVL1, SLC3A2,
Protein Size: 507

Poids moléculaire: 56 kDa

ID gène: 8140

NCBI Accession: NM_003486, NP_003477

UniProt: Q01650