LILRB2 anticorps (C-Term)
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- Antigène Voir toutes LILRB2 Anticorps
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LILRB2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- MDTRAAASEA PQDVTYAQLH SLTLRRKATE PPPSQEREPP AEPSIYATLA
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against LILRB2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product LILRB2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 598 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
- Autre désignation
- LILRB2 (LILRB2 Produits)
- Synonymes
- anticorps CD85D, anticorps ILT-4, anticorps ILT4, anticorps LIR-2, anticorps LIR2, anticorps MIR-10, anticorps MIR10, anticorps leukocyte immunoglobulin-like receptor subfamily A member 3, anticorps leukocyte immunoglobulin like receptor B2, anticorps LOC100433990, anticorps LILRB2
- Sujet
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This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD85D, ILT4, LILRA6, LIR-2, LIR2, MIR-10, MIR10
Protein Interaction Partner: PTPN6, FCGR1A, HLA-F, HLA-G, HLA-C, HLA-B, HLA-A,
Protein Size: 598 - Poids moléculaire
- 65 kDa
- ID gène
- 10288
- NCBI Accession
- NM_005874, NP_005865
- UniProt
- Q8N423
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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