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PIK3C2A anticorps (C-Term)
PIK3C2A
Reactivité: Humain, Souris, Rat, Chien, Porc, Cheval, Lapin, Poisson zèbre (Danio rerio)
WB
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN2498949
Détail du produit anti-PIK3C2A anticorps
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Antigène
Voir toutes PIK3C2A Anticorps
PIK3C2A
(Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))
Épitope
Tous les épitopes à travers PIK3C2A Anticorps.
C-Term
Reactivité
Humain, Souris, Rat, Chien, Porc, Cheval, Lapin, Poisson zèbre (Danio rerio)
Hôte
Toutes les hôtes sur PIK3C2A Anticorps
Lapin
Clonalité
Toutes les clonalités sur PIK3C2A Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers PIK3C2A Anticorps
Cet anticorp PIK3C2A est non-conjugé
Application
Tous les applications à travers PIK3C2A Anticorps.
Western Blotting (WB)
Séquence
PNPYVKTYLL PDNHKTSKRK TKISRKTRNP TFNEMLVYSG YSKETLRQRE
Homologie
Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 92%
Attributs du produit
This is a rabbit polyclonal antibody against PIK3C2A. It was validated on Western Blot.
Purification
Affinity Purified
Immunogène
The immunogen is a synthetic peptide directed towards the C-terminal region of human PIK3C2A
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeat freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Détails sur PIK3C2A
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Antigène
PIK3C2A
(Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))
Autre désignation
PIK3C2A (PIK3C2A Produits )
Synonymes
anticorps CPK, anticorps PI3-K-C2(ALPHA), anticorps PI3-K-C2A, anticorps cpk, anticorps pi3-k-c2a, anticorps Cpk-m, anticorps PI3KC2, anticorps sb:cb156, anticorps si:dkey-24l11.7, anticorps wu:fc02a04, anticorps phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha, anticorps phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha, anticorps phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha S homeolog, anticorps phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, anticorps PIK3C2A, anticorps Pik3c2a, anticorps pik3c2a, anticorps pik3c2a.S, anticorps LOC100548137
Sujet
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. Alias Symbols: CPK, PI3-K-C2A, PI3-K-C2(ALPHA) Protein Size: 1306
Poids moléculaire
143 kDa
ID gène
5286
NCBI Accession
NM_002645 , NP_002636
UniProt
O00443
Pathways
EGFR Signaling Pathway , Inositol Metabolic Process , Platelet-derived growth Factor Receptor Signaling
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