CDK7 anticorps (Middle Region)
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- Antigène Voir toutes CDK7 Anticorps
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Boeuf (Vache), Chien, Cheval, Porc, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CDK7 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TQALKMKYFS NRPGPTPGCQ LPRPNCPVET LKEQSNPALA IKRKRTEALE
- Réactivité croisée
- Boeuf (Vache), Chien, Humain, Porc, Rat (Rattus)
- Homologie
- Cow: 80%, Dog: 86%, Guinea Pig: 78%, Horse: 86%, Human: 100%, Pig: 86%, Rat: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against CDK7. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CDK7
- Top Product
- Discover our top product CDK7 Anticorps primaire
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- Indications d'application
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WB Suggested Anti-CDK7 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:12500
Positive Control: THP-1 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Commentaires
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Antigen size: 346 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
- Autre désignation
- CDK7 (CDK7 Produits)
- Synonymes
- anticorps CAK1, anticorps CDKN7, anticorps HCAK, anticorps MO15, anticorps STK1, anticorps p39MO15, anticorps AI323415, anticorps AI528512, anticorps C230069N13, anticorps Cdkn7, anticorps Crk4, anticorps CD 7, anticorps CDK7, anticorps CG3319, anticorps DmCDK7, anticorps DmCdk7, anticorps DmMO15, anticorps DmMo15, anticorps Dmcdk7, anticorps Dmel\\CG3319, anticorps Mo15, anticorps cdk-7, anticorps cdk7, anticorps dCdk7, anticorps p40[MO15], anticorps p40MO15, anticorps stk1, anticorps zgc:85821, anticorps cak1, anticorps cdkn7, anticorps p39mo15, anticorps cyclin dependent kinase 7, anticorps cyclin-dependent kinase 7, anticorps Cyclin-dependent kinase 7, anticorps cyclin-dependent kinase 7 L homeolog, anticorps CDK7, anticorps Cdk7, anticorps cdk7.L, anticorps cdk7
- Sujet
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CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CAK1, CDKN7, MO15, STK1, p39MO15, HCAK
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, GTF2H4, GTF2H3, GTF2H2, GTF2H1, ERCC5, ERCC3, ERCC2, CDK7, CCNH, ATP2B4, A2M, GTF2H5, SRPK2, SRPK1, MNAT1, TP53, CDK2, CTD, MBP, CDK1, CCNB1, CCNA2, Dlg4, UVSSA, HSP90AA1, HSD17B4, HLA-DQA1, SUPT5H, POLR2A, GTF2E2, GTF2E1, CDK9, APP
Protein Size: 346 - Poids moléculaire
- 39 kDa
- ID gène
- 1022
- NCBI Accession
- NM_001799, NP_001790
- UniProt
- P50613
- Pathways
- Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
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