PIK3CA anticorps (Center)
Aperçu rapide pour PIK3CA anticorps (Center) (ABIN2793321)
Antigène
Voir toutes PIK3CA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 504-533, Center
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Fonction
- Rabbit Anti-Human PI3KCA (Center) Antibody
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Immunogène
- This PI3KCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 504-533 amino acids from the Central region of human PI3KCA.
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Isotype
- Ig Fraction
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Indications d'application
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-PIK3CA Antibody (Center) Pab , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.570 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
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Autre désignation
- PI3KCA
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Sujet
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Target Description: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
Gene Symbol: PIK3CA
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Poids moléculaire
- 124284 Da
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ID gène
- 5290
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UniProt
- P42336
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Pathways
- Signalisation PI3K-Akt, Signalisation RTK, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling
Antigène
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