KHDRBS1 anticorps (AA 101-200) (Alexa Fluor 594)

N° du produit ABIN2806175

Détail du produit anti-KHDRBS1 anticorps (Alexa Fluor 594)

Antigène: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Épitope: AA 101-200

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KHDRBS1 est conjugé à/à la Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SAM68

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur KHDRBS1

Antigène: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Autre désignation: SAM68 (KHDRBS1 Produits)

Synonymes: anticorps Sam68, anticorps p62, anticorps p68, anticorps fj90g10, anticorps khdrbs1, anticorps wu:fa18g12, anticorps wu:fa56c01, anticorps wu:fc91b01, anticorps wu:fj90g10, anticorps zgc:113899, anticorps KHDRBS1, anticorps P62, anticorps khdrbs1l, anticorps sb:cb97, anticorps wu:fb07d11, anticorps wu:fi43c05, anticorps zgc:85948, anticorps KH RNA binding domain containing, signal transduction associated 1, anticorps KH domain containing, RNA binding, signal transduction associated 1a, anticorps KH domain containing, RNA binding, signal transduction associated 1, anticorps KH domain containing, RNA binding, signal transduction associated 1 S homeolog, anticorps KH domain containing, RNA binding, signal transduction associated 1b, anticorps KHDRBS1, anticorps khdrbs1a, anticorps khdrbs1, anticorps Khdrbs1, anticorps khdrbs1.S, anticorps khdrbs1b

Sujet:

Synonyms: FLJ34027, GAP associated tyrosine phosphoprotein p62, GAP-associated tyrosine phosphoprotein p62, KH domain containing RNA binding signal transduction associated 1, KH domain-containing, KHDR1_HUMAN, KHDRBS1, p21 Ras GTPase activating protein associated p62, p21 Ras GTPase-activating protein-associated p62, p62, p68, RNA-binding, Sam68, signal transduction-associated protein 1, Src associated in mitosis 68 kDa protein, Src-associated in mitosis 68 kDa protein.

Background: Sam 68 is a protein that is phosphorylated on tyrosine and functions as a substrate for Src family tyrosine kinases during mitosis. Sam 68 also associates with several SH2 and SH3 domain-containing signaling proteins, such as GRB2 and PLC ?. Originally cloned as Ras GAP-associated p62, further investigations have shown that Sam 68 and Ras GAP-associated p62 are not antigenically related, nor are they encoded by the same gene. Like Sam 68, the Sam 68-like mammalian proteins, SLM-1 and SLM-2, demonstrate RNA binding activity. Also like Sam 68, SLM-1 is tyrosine phosphorylated and functions as an adapter protein for signaling molecules, including GRB2, PLC ?, Fyn and Ras GAP. SLM-2 is not tyrosine phosphorylated, nor does it appear to associate with GRB2, PLC ?, Fyn or Ras GAP, indicating that SLM-2 may not be an adapter protein for these proteins.

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy