KHDRBS1 anticorps (AA 259-291)

N° du produit ABIN6242416

Détail du produit anti-KHDRBS1 anticorps

Antigène: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Épitope: AA 259-291

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KHDRBS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KHDRBS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 259-291 amino acids from the Central region of human KHDRBS1.

Clone: RB54155

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur KHDRBS1

Antigène: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Autre désignation: KHDRBS1 (KHDRBS1 Produits)

Synonymes: anticorps Sam68, anticorps p62, anticorps p68, anticorps fj90g10, anticorps khdrbs1, anticorps wu:fa18g12, anticorps wu:fa56c01, anticorps wu:fc91b01, anticorps wu:fj90g10, anticorps zgc:113899, anticorps KHDRBS1, anticorps P62, anticorps khdrbs1l, anticorps sb:cb97, anticorps wu:fb07d11, anticorps wu:fi43c05, anticorps zgc:85948, anticorps KH RNA binding domain containing, signal transduction associated 1, anticorps KH domain containing, RNA binding, signal transduction associated 1a, anticorps KH domain containing, RNA binding, signal transduction associated 1, anticorps KH domain containing, RNA binding, signal transduction associated 1 S homeolog, anticorps KH domain containing, RNA binding, signal transduction associated 1b, anticorps KHDRBS1, anticorps khdrbs1a, anticorps khdrbs1, anticorps Khdrbs1, anticorps khdrbs1.S, anticorps khdrbs1b

Sujet: Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export. Positively regulates the association of constitutive transport element (CTE)-containing mRNA with large polyribosomes and translation initiation. According to some authors, is not involved in the nucleocytoplasmic export of unspliced (CTE)-containing RNA species according to (PubMed:< a href="http://www.uniprot.org/citations/22253824" target="_blank">22253824).

Poids moléculaire: 48227

UniProt: Q07666

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy