STAT2 anticorps (pTyr690) (AbBy Fluor® 594)
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- Antigène Voir toutes STAT2 Anticorps
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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Épitope
- pTyr690
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp STAT2 est conjugé à/à la AbBy Fluor® 594
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Specificité
- This phosphorylation site is homologous to that of Tyr689 in Mouse and Tyr690 in Rat.
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690
- Isotype
- IgG
- Top Product
- Discover our top product STAT2 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
- Autre désignation
- Stat2 (STAT2 Produits)
- Synonymes
- anticorps wu:fj84d07, anticorps p113, anticorps stat2, anticorps 1600010G07Rik, anticorps AW496480, anticorps ISGF-3, anticorps P113, anticorps STAT113, anticorps signal transducer and activator of transcription 2, anticorps AGAP000099-PA, anticorps stat2, anticorps STAT2, anticorps Stat2
- Sujet
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Synonyms: P113, ISGF-3, STAT113, Signal transducer and activator of transcription 2, STAT2
Background: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
- ID gène
- 6773
- UniProt
- P52630
- Pathways
- Signalistation JAK/STAT, Hepatitis C, CXCR4-mediated Signaling Events
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