Osteoactivin anticorps
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- Antigène Voir toutes Osteoactivin (GPNMB) Anticorps
- Osteoactivin (GPNMB)
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Osteoactivin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain
- Attributs du produit
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Rabbit Polyclonal antibody to GPNMB (glycoprotein (transmembrane) nmb)
GPNMB antibody [N2C2], Internal - Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human GPNMB. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product GPNMB Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: SKBR3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Agent conservateur
- Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- Osteoactivin (GPNMB)
- Autre désignation
- glycoprotein nmb (GPNMB Produits)
- Synonymes
- anticorps HGFIN, anticorps NMB, anticorps DC-HIL, anticorps Dchil, anticorps ipd, anticorps glycoprotein nmb, anticorps glycoprotein (transmembrane) nmb, anticorps glycoprotein nmb L homeolog, anticorps Gpnmb, anticorps GPNMB, anticorps gpnmb.L
- Sujet
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The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Membrane, Single-pass type I membrane protein (Potential) , Melanosome - Poids moléculaire
- 64 kDa
- ID gène
- 10457
- UniProt
- Q14956
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