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PLIN1 anticorps (N-Term)

PLIN1 Reactivité: Humain, Souris, Rat WB, IHC (p), IHC (fro) Hôte: Cobaye Polyclonal unconjugated
N° du produit ABIN285897
  • Antigène Voir toutes PLIN1 Anticorps
    PLIN1 (Perilipin 1 (PLIN1))
    Épitope
    • 16
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 51
    • 51
    • 43
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 60
    • 4
    • 2
    • 2
    • 1
    Cobaye
    Clonalité
    • 56
    • 13
    Polyclonal
    Conjugué
    • 28
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp PLIN1 est non-conjugé
    Application
    • 54
    • 18
    • 16
    • 14
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Stabilized antiserum
    Immunogène
    Perilipin antibody was raised in guinea pig using duplicated N-terminus of perilipin as the immunogen.
    Isotype
    IgG1
    Top Product
    Discover our top product PLIN1 Anticorps primaire
  • Indications d'application
    IHC-F: 1:100-200, IHC-P: 1:100-1:200, WB: 1:2,000
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Supplied as whole antiserum with 0.09 % NaN3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C
  • Bae, Hong, Lee, Jang, Lee, Choe, Offermanns, He, Lee, Koh: "Angiopoietin-2-integrin α5β1 signaling enhances vascular fatty acid transport and prevents ectopic lipid-induced insulin resistance." dans: Nature communications, Vol. 11, Issue 1, pp. 2980, (2020) (PubMed).

    Kong, Ji, Jeon, Han, Han, Lee, Lee, Jang, Choe, Baes, Kim: "Spatiotemporal contact between peroxisomes and lipid droplets regulates fasting-induced lipolysis via PEX5." dans: Nature communications, Vol. 11, Issue 1, pp. 578, (2020) (PubMed).

    Choi, Bae, Jeong, Park, Cho, Hong, Lee, Lee, Park, Suh, Choi, Yang, Jang, Onder, Moon, Jeong, Adams, Kim, Ludewig, Song, Lim, Koh: "YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells." dans: Nature communications, Vol. 11, Issue 1, pp. 519, (2020) (PubMed).

    Liu, Li, Li, Wang, Ding, Wang, Ye, Jin, Hou, Fang, Shu: "TREM2 regulates obesity-induced insulin resistance via adipose tissue remodeling in mice of high-fat feeding." dans: Journal of translational medicine, Vol. 17, Issue 1, pp. 300, (2020) (PubMed).

    An, Crewe, Asterholm, Sun, Chen, Zhang, Shao, Funcke, Zhang, Straub, Klein, Kusminski, Scherer: "Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity." dans: Nature metabolism, Vol. 1, Issue 12, pp. 1243-1257, (2019) (PubMed).

    Crewe, Joffin, Rutkowski, Kim, Zhang, Towler, Gordillo, Scherer: "An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State." dans: Cell, Vol. 175, Issue 3, pp. 695-708.e13, (2019) (PubMed).

    Hepler, Shan, Zhang, Henry, Shao, Vishvanath, Ghaben, Mobley, Strand, Hon, Gupta: "Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice." dans: eLife, Vol. 7, (2019) (PubMed).

    Monks, Orlicky, Stefanski, Libby, Bales, Rudolph, Johnson, Sherk, Jackman, Williamson, Carlson, MacLean, McManaman: "Maternal obesity during lactation may protect offspring from high fat diet-induced metabolic dysfunction." dans: Nutrition & diabetes, Vol. 8, Issue 1, pp. 18, (2019) (PubMed).

    Tran, Fitzgibbons, Min, DeSouza, Corvera: "Distinct adipocyte progenitor cells are associated with regional phenotypes of perivascular aortic fat in mice." dans: Molecular metabolism, Vol. 9, pp. 199-206, (2019) (PubMed).

    Xu, Li, Wu, Li, Zhao, Yu, Huang, Ferguson, Parton, Yang, Li: "Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions." dans: The Journal of cell biology, Vol. 217, Issue 3, pp. 975-995, (2019) (PubMed).

    Zhang, Hao, Shao, Nham, An, Wang, Zhu, Kusminski, Hassan, Gupta, Zhai, Sun, Scherer, Oz: "An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents." dans: Cell metabolism, Vol. 27, Issue 1, pp. 252-262.e3, (2019) (PubMed).

    Shao, Vishvanath, Busbuso, Hepler, Shan, Sharma, Chen, Yu, An, Zhu, Holland, Gupta: "De novo adipocyte differentiation from Pdgfrβ+ preadipocytes protects against pathologic visceral adipose expansion in obesity." dans: Nature communications, Vol. 9, Issue 1, pp. 890, (2018) (PubMed).

    Fischer, Seki, Lim, Nakamura, Andersson, Yang, Honek, Wang, Gao, Chen, Samani, Zhang, Miyake, Oyadomari, Yasue, Li, Zhang, Liu, Cao: "A miR-327-FGF10-FGFR2-mediated autocrine signaling mechanism controls white fat browning." dans: Nature communications, Vol. 8, Issue 1, pp. 2079, (2018) (PubMed).

    Shin, Hwang, Choe, Park, Ji, Kim, Lee, Choi, Ching, Kovalik, Kim: "Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation." dans: Nature communications, Vol. 8, Issue 1, pp. 1087, (2018) (PubMed).

    Hepler, Shao, Xia, Ghaben, Pearson, Vishvanath, Sharma, Morley, Holland, Gupta: "Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice." dans: eLife, Vol. 6, (2018) (PubMed).

    Shao, Hepler, Vishvanath, MacPherson, Busbuso, Gupta: "Fetal development of subcutaneous white adipose tissue is dependent on Zfp423." dans: Molecular metabolism, Vol. 6, Issue 1, pp. 111-124, (2018) (PubMed).

    Lim, Hosaka, Nakamura, Cao: "Co-option of pre-existing vascular beds in adipose tissue controls tumor growth rates and angiogenesis." dans: Oncotarget, Vol. 7, Issue 25, pp. 38282-38291, (2018) (PubMed).

    Park, Kim, Sun, An, Gu, Scherer: "VEGF-A-Expressing Adipose Tissue Shows Rapid Beiging and Enhanced Survival After Transplantation and Confers IL-4-Independent Metabolic Improvements." dans: Diabetes, Vol. 66, Issue 6, pp. 1479-1490, (2017) (PubMed).

    An, Sun, Joffin, Zhang, Deng, Donzé, Kusminski, Scherer: "Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis." dans: eLife, Vol. 6, (2017) (PubMed).

    Ye, Wang, Tao, Vishvanath, Shao, McDonald, Gupta, Scherer: "Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase." dans: Molecular metabolism, Vol. 4, Issue 11, pp. 771-8, (2015) (PubMed).

  • Antigène
    PLIN1 (Perilipin 1 (PLIN1))
    Autre désignation
    Perilipin (PLIN1 Produits)
    Synonymes
    anticorps FPLD4, anticorps PERI, anticorps PLIN, anticorps PERIA, anticorps Plin, anticorps 6030432J05Rik, anticorps Peri, anticorps peri, anticorps plin, anticorps perilipin, anticorps LOC692833, anticorps perilipin 1, anticorps perilipin, anticorps perilipin 1 L homeolog, anticorps PLIN1, anticorps Plin1, anticorps plin1, anticorps LOC692833, anticorps plin1.L
    Sujet
    Perilipins build a family of phosphoproteins. The predominant forms in adipocytes, perilipin A and B arise by alternative RNA splicing from a single gene, generating polypeptides of 57 and 46 kDa, respectively. The N-terminus, however, remains unchanged. The antiserum reacts specifically with perilipins (A and B) located at the surface of intracellular storage lipid droplets present e.g. in the adrenal gland, adipocytes of white and brown adipose tissue and cultured cells such as 3T3-L1 adipocytes and cultured steroidogenic adrenal cortical and Leydig cells.
    Pathways
    Lipid Metabolism
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