CTNNB1 anticorps (pSer45, pThr41)

N° du produit ABIN3020172

Détail du produit anti-CTNNB1 anticorps

Antigène: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Épitope: pSer45, pThr41

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTNNB1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding T41/S45 of human CTNNB1

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CTNNB1

Antigène: CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

Autre désignation: CTNNB1 (CTNNB1 Produits)

Synonymes: anticorps Jup, anticorps LOC100217813, anticorps CTNNB1, anticorps CTNNB, anticorps Bfc, anticorps Catnb, anticorps Mesc, anticorps ctnnb, anticorps id:ibd2058, anticorps wu:fb73e10, anticorps wu:fi81c06, anticorps wu:fk25h01, anticorps ctnnb1, anticorps CHBCAT, anticorps MRD19, anticorps armadillo, anticorps beta-catenin, anticorps catenin beta 1, anticorps catenin (cadherin associated protein), beta 1, anticorps catenin (cadherin-associated protein), beta 1, anticorps catenin beta 1 S homeolog, anticorps catenin beta 1 L homeolog, anticorps CTNNB1, anticorps Ctnnb1, anticorps ctnnb1, anticorps ctnnb1.S, anticorps ctnnb1.L

Sujet: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.,CTNNB,MRD19,armadillo,beta Catenin,CTNNB1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cell Adhesion,Cadherins,Tight Junctions,Cytoskeleton,Microfilaments,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Neuroscience,Stem Cells,Cardiovascular,Angiogenesis,Protein phosphorylation,CTNNB1

Poids moléculaire: 9 kDa/85 kDa

ID gène: 1499

UniProt: P35222

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2