JAK2 anticorps (pTyr1007)

N° du produit ABIN3020271

Détail du produit anti-JAK2 anticorps

Antigène: JAK2 (Janus Kinase 2 (JAK2))

Épitope: pTyr1007

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAK2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Souris

Attributs du produit: Phosphorylated Antibodies

Immunogène: A phospho specific peptide corresponding to residues surrounding Y1007 of human Phospho-JAK2-Y1007

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-JAK2 (ABIN3020271)

He, Yang, Li, Shao, Wei, Wang, Li, Xu: "Exogenous spermine ameliorates high glucose-induced cardiomyocytic apoptosis via decreasing reactive oxygen species accumulation through inhibiting p38/JNK and JAK2 pathways." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 12, pp. 15537-49, (2016) (PubMed).

Détails sur JAK2

Antigène: JAK2 (Janus Kinase 2 (JAK2))

Autre désignation: JAK2 (JAK2 Produits)

Synonymes: anticorps JAK2bCA, anticorps jak2, anticorps JTK10, anticorps THCYT3, anticorps AI504024, anticorps C81284, anticorps Fd17, anticorps JAK-2, anticorps Janus kinase 2b, anticorps Janus kinase 2, anticorps jak2b, anticorps JAK2, anticorps Jak2

Sujet: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.,JAK2,JTK10,THCYT3,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Phosphorylation,Cancer,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Cell Cycle,Cell cycle inhibitors,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Protein phosphorylation,JAK2

Poids moléculaire: 130 kDa

ID gène: 3717

UniProt: O60674

Pathways: Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response