SUMO1 anticorps
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- Antigène Voir toutes SUMO1 Anticorps
- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
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Reactivité
- Humain, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SUMO1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Attributs du produit
- This antibody is specific to SUMO1 and shows no cross-reaction with either SUMO2 or SUMO3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO1 protein localizes to the nuclear membrane.
- Purification
- Protein G affinity chromatography
- Immunogène
- Recombinant human SUMO1 protein was used as the immunogen for this antibody.
- Clone
- SM1-495
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product SUMO1 Anticorps primaire
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- Indications d'application
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The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,WB: 0.5-1 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1),Prediluted format : incubate for 30 min at RT (2) - Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the SUMO1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Antigène
- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
- Autre désignation
- SUMO1 (SUMO1 Produits)
- Synonymes
- anticorps DAP1, anticorps GMP1, anticorps OFC10, anticorps PIC1, anticorps SENP2, anticorps SMT3, anticorps SMT3C, anticorps SMT3H3, anticorps UBL1, anticorps hm:zeh0670, anticorps wu:fb74c02, anticorps wu:fd12c02, anticorps zgc:65934, anticorps zgc:85634, anticorps SUMO1, anticorps dap1, anticorps gmp1, anticorps ofc10, anticorps pic1, anticorps senp2, anticorps smt3, anticorps smt3c, anticorps sumo-1, anticorps sumo1, anticorps ubl1, anticorps xsumo-1, anticorps xsumo1, anticorps ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1, anticorps ATSUMO1, anticorps F10M23.180, anticorps F10M23_180, anticorps SMALL UBIQUITIN-LIKE MODIFIER 1, anticorps SUM1, anticorps SUMO 1, anticorps small ubiquitin-like modifier 1, anticorps pigSUMO1, anticorps SENTRIN, anticorps SMTP3, anticorps SUMO-1, anticorps Smt3C, anticorps Ubl1, anticorps small ubiquitin-like modifier 1, anticorps small ubiquitin-like modifier 1 S homeolog, anticorps small ubiquitin-related protein 1, anticorps SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), anticorps SMT3 suppressor of mif two 3 homolog 1 (yeast), anticorps small ubiquitin-like modifier 1 L homeolog, anticorps Sumo1, anticorps SUMO1, anticorps sumo1, anticorps sumo1.S, anticorps sumo-1, anticorps sumo1.L
- Sujet
- This antibody is specific to SUMO1 and shows no cross-reaction with either SUMO2 or SUMO3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO1, 2 and 3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO1 protein localizes to the nuclear membrane.
- ID gène
- 7341
- Pathways
- M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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