FHIT anticorps (AA 1-147)
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- Antigène Voir toutes FHIT Anticorps
- FHIT (Fragile Histidine Triad (FHIT))
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Épitope
- AA 1-147
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FHIT est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogène
- Human partial recombinant protein (AA 1-147) was used as the immunogen for this FHIT antibody.
- Isotype
- IgG
- Top Product
- Discover our top product FHIT Anticorps primaire
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- Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the FHIT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the FHIT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- FHIT (Fragile Histidine Triad (FHIT))
- Autre désignation
- FHIT (FHIT Produits)
- Synonymes
- anticorps AP3Aase, anticorps FRA3B, anticorps FHIT, anticorps zgc:73176, anticorps AW045638, anticorps Fra14A2, anticorps LOC100223655, anticorps fragile histidine triad, anticorps fragile histidine triad gene, anticorps fragile histidine triad protein, anticorps fragile histidine triad L homeolog, anticorps FHIT, anticorps Fhit, anticorps fhit, anticorps PY07476, anticorps fhit.L
- Sujet
- Bis(5'-adenosyl)-triphosphatase, also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene. This gene, a member of the histidine triad gene family, encodes a diadenosine P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3p14.2, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Furthermore, FHIT has been shown to synergize with VHL, another tumor suppressor, in protecting against chemically - induced lung cancer. It also acts as a tumor suppressor of HER2/neu driven breast cancer.
- ID gène
- 2272
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