HSPE1 anticorps (C-Term)

N° du produit ABIN3031141

Détail du produit anti-HSPE1 anticorps

Antigène: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPE1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human Heat shock protein 10 (VVLDDKDYFLFRDGDILGKYVD) was used as the immunogen for this HSP10 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the HSP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the HSP10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur HSPE1

Antigène: HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))

Autre désignation: HSP10 (HSPE1 Produits)

Synonymes: anticorps CPN10, anticorps EPF, anticorps GROES, anticorps HSP10, anticorps groS, anticorps Cpn10, anticorps cpn10, anticorps zgc:86747, anticorps hspe1, anticorps MGC89647, anticorps HSPE1, anticorps MITOCHONDRIAL CHAPERONIN 10, anticorps T15D22.2, anticorps T15D22_2, anticorps chaperonin 10, anticorps Dmel\\CG11267, anticorps Hsp10, anticorps anon-WO0118547.175, anticorps hsp10, anticorps crpB, anticorps chpS, anticorps 10kDa, anticorps mt-cpn10, anticorps heat shock protein family E (Hsp10) member 1, anticorps molecular chaperone GroES, anticorps chaperonin 10 kDa, anticorps chaperonin, 10 kDa, anticorps chaperonin-10 kDa, anticorps heat shock protein family E member 1, anticorps heat shock 10 protein 1, anticorps heat shock protein family E (Hsp10) member 1 L homeolog, anticorps heat shock 10kDa protein 1 (chaperonin 10) pseudogene, anticorps 10 kd chaperonin, anticorps chaperonin 10, anticorps Hsp10p, anticorps co-chaperonin 10, mitochondrial, anticorps CG11267 gene product from transcript CG11267-RA, anticorps co-chaperonin GroES, anticorps mitochondrial heat shock protein Hsp10 (predicted), anticorps chaperonin GroS, anticorps Hsp10 10 kDa chaperonin GROES, anticorps mitochondrial heat shock protein Hsp10, anticorps heat shock protein 10, anticorps heat shock protein 1 (chaperonin 10), anticorps heat shock 10kDa protein 1 (chaperonin 10), anticorps HSPE1, anticorps groES, anticorps groES2, anticorps TP01_0190, anticorps Cag_1167, anticorps Bm1_56470, anticorps Hspe1, anticorps hspe1, anticorps hspe1.L, anticorps LOC452179, anticorps Cpn10, anticorps CPN10, anticorps HSP10, anticorps CG11267, anticorps hsp10, anticorps groS

Sujet: Heat shock 10 kDa protein 1, also called CPN10, GROES, and HSP10, is a protein that in humans is encoded by the HSPE1 gene. It is a heptameric ring of identical 10.4-kD subunits that binds to each end of GroEL to form a symmetric, functional heterodimer. The transcriptional activity of the promoter fragment in the HSP60 direction is approximately twice that in the HSP10 direction under normal growth conditions, upon heat shock, promoter activity in either direction increased by a factor of approximately 12. Mutational drifts performed in vitro with 4 different enzymes indicated the HSP10 overexpression doubled the number of accumulating mutations, and promoted the folding of enzyme variants carrying mutations in the protein core and/or mutations with higher destabilizing effects.

UniProt: P61604

Pathways: Positive Regulation of Endopeptidase Activity