WNT1 anticorps (N-Term)

N° du produit ABIN3042350

Détail du produit anti-WNT1 anticorps

Antigène: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Épitope: AA 45-74, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Proto-oncogene Wnt-1(WNT1) detection. Tested with WB in Human.

Séquence: NLLTDSKSLQ LVLEPSLQLL SRKQRRLIRQ

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Proto-oncogene Wnt-1(WNT1) detection. Tested with WB in Human.
Gene Name: wingless-type MMTV integration site family, member 1
Protein Name: Proto-oncogene Wnt-1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Wnt1 (45-74aa NLLTDSKSLQLVLEPSLQLLSRKQRRLIRQ), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Wnt1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-WNT1 (ABIN3042350)

Mi, Li, Zhang, Zhao, Peng, Yang, Zheng: "MicroRNA-139-5p regulates C2C12 cell myogenesis through blocking Wnt/β-catenin signaling pathway." dans: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 93, Issue 1, pp. 8-15, (2015) (PubMed).

Dong, Duan, Han, Zhang, Wu: "Suppression of wingless-type MMTV integration site family, member 1 expression by small interfering RNA inhibits U251 glioma cell growth in vitro." dans: Oncology letters, Vol. 9, Issue 1, pp. 81-85, (2014) (PubMed).

Détails sur WNT1

Antigène: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Autre désignation: WNT1 (WNT1 Produits)

Synonymes: anticorps Xint-1, anticorps Xwnt1, anticorps int-1, anticorps int1, anticorps wnt-1, anticorps wnt1-a, anticorps Int-1, anticorps Wnt-1, anticorps sw, anticorps swaying, anticorps BMND16, anticorps INT1, anticorps OI15, anticorps Int1, anticorps WNT-1, anticorps sb:eu647, anticorps zgc:194464, anticorps zgc:194478, anticorps WNT1, anticorps Wnt family member 1, anticorps Wnt family member 1 L homeolog, anticorps wingless-type MMTV integration site family, member 1, anticorps WNT1, anticorps wnt1.L, anticorps Wnt1, anticorps wnt1

Sujet: Wingless-type MMIV integration site family, member 1 is a protein that in humans is encoded by the WNT1 gene. This gene is a member of the WNT gene family. The gene was assigned to human chromosome 12q13.12. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. The Wnt1 protein functions in the induction of the mesencephalon and cerebellum. However, the gene mutations might not have a significant role in Joubert syndrome.

Synonyms: BMND16 antibody|INT1 antibody|OI15 antibody|oncogene Int1 antibody|Proto oncogene protein Wnt 1 antibody|Proto-oncogene Int-1 homolog antibody|Proto-oncogene Wnt-1 antibody|Wingless type MMTV integration site family member 1 antibody|wingless-type MMTV integration site family, member 1 (oncogene INT1) antibody|Wnt 1 antibody|wnt1 antibody|WNT1_HUMAN antibody

ID gène: 7471

UniProt: P04628

Pathways: Signalisation WNT, Dopaminergic Neurogenesis