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DDR2 anticorps (C-Term)

DDR2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3043008
  • Antigène Voir toutes DDR2 Anticorps
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    Épitope
    • 9
    • 9
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 834-855, C-Term
    Reactivité
    • 42
    • 25
    • 2
    • 1
    Humain
    Hôte
    • 48
    • 7
    Lapin
    Clonalité
    • 48
    • 7
    Polyclonal
    Conjugué
    • 29
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DDR2 est non-conjugé
    Application
    • 41
    • 34
    • 21
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    Rabbit IgG polyclonal antibody for Discoidin domain-containing receptor 2(DDR2) detection. Tested with WB in Human.
    Séquence
    RDTKNRPSFQ EIHLLLLQQG DE
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Discoidin domain-containing receptor 2(DDR2) detection. Tested with WB in Human.
    Gene Name: discoidin domain receptor tyrosine kinase 2
    Protein Name: Discoidin domain-containing receptor 2
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of human DDR2(834-855aa RDTKNRPSFQEIHLLLLQQGDE), different from the related mouse sequence by three amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product DDR2 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for DDR2 is approximately 5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Antigène
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    Autre désignation
    DDR2 (DDR2 Produits)
    Synonymes
    anticorps MIG20a, anticorps NTRKR3, anticorps TKT, anticorps TYRO10, anticorps AW495251, anticorps Ntrkr3, anticorps tyro10, anticorps DDR2, anticorps Tyro10, anticorps ddr2, anticorps si:ch211-193c2.1, anticorps discoidin domain receptor tyrosine kinase 2, anticorps discoidin domain receptor family, member 2, anticorps discoidin domain receptor family, member 2, like, anticorps DDR2, anticorps Ddr2, anticorps ddr2l
    Sujet
    DDR2(Discoidin domain receptor family, member 2) also known as NTRKR3 or TKT, is a human gene. Ddr2 protein was detected in most mouse tissues examined. Highest levels of phosphorylated Ddr2 were detected in lung, ovary, and skin, which did not correlate with Ddr2 protein levels. The DDR2 gene is mapped 1q23.3. Receptor tyrosine kinases(RTKs) play a key role in the communication of cells with their microenvironment.Using in situ hybridization with 1-week-old mice, Labrador et al.(2001) found that Ddr2 was expressed along chondrocyte columns in the proliferative region of the growth plate.Ddr2mRNA was also present, although dispersed, at areas of calcified cartilage in the cartilage-bone junction, as well as in the trabecular bone surface. Bargal et al.(2009) also identified a splice site mutation in the DDR2 gene, which resulted in the skipping of exon 17, in one of the Jewish families with SMED-SL originally reported by Borochowitz et al.(1993).

    Synonyms: CD167 antigen-like family member B antibody|CD167b antibody|CD167b antigen antibody|Cell migration inducing protein 20 antibody|DDR 2 antibody|DDR2 antibody|DDR2_HUMAN antibody|Discoidin domain containing receptor 2 antibody|Discoidin domain receptor 2 antibody|Discoidin domain receptor family member 2 antibody|discoidin domain receptor tyrosine kinase 2 antibody|Discoidin domain-containing receptor 2 antibody|discoidin domain-containing receptor tyrosine kinase 2 antibody|Hydroxyaryl protein kinase antibody|MIG20a antibody|Migration inducing gene 16 protein antibody|Neurotrophic tyrosine kinase antibody|Neurotrophic tyrosine kinase receptor related 3 antibody|NTRKR 3 antibody|NTRKR3 antibody|Receptor protein tyrosine kinase TKT antibody|Receptor protein-tyrosine kinase TKT antibody|Receptor related 3 antibody|receptor-related 3 antibody|TKT antibody|TYRO 10 antibody|TYRO10 antibody|Tyrosine kinase receptor related to neurotrophic TRK antibody|Tyrosine protein kinase TYRO 10 antibody|Tyrosine protein kinase TYRO10 antibody|Tyrosine-protein kinase TYRO10 antibody|Tyrosylprotein kinase antibody
    UniProt
    Q16832
    Pathways
    Signalisation RTK
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