Serotonin Receptor 1A anticorps (C-Term)

N° du produit ABIN3044241

Détail du produit anti-Serotonin Receptor 1A anticorps

Antigène: Serotonin Receptor 1A (HTR1A)

Épitope: AA 404-422, C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 1A(HTR1A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: NKDFQNAFKK IIKCKFCRQ

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for 5-hydroxytryptamine receptor 1A(HTR1A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: 5-hydroxytryptamine(serotonin) receptor 1A, G protein-coupled
Protein Name: 5-hydroxytryptamine receptor 1A(5-HT-1A/5-HT1A)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT1A Receptor(404-422aa NKDFQNAFKKIIKCKFCRQ), different from the related rat and mouse sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Serotonin Receptor 1A

Antigène: Serotonin Receptor 1A (HTR1A)

Autre désignation: HTR1A (HTR1A Produits)

Synonymes: anticorps 5-HT-dro2A, anticorps 5-HT1ADro, anticorps 5-HT[1A]Dro, anticorps 5-HT[[1ADro]], anticorps 5-HT[[1A]], anticorps 5-HT[[1A]]DRO, anticorps 5HT-R2A, anticorps 5HT-dro2A, anticorps 5HT-drp[[2A]], anticorps 5HT1A, anticorps 5HT[[1ADro]], anticorps 5htdro2a, anticorps CG16720, anticorps DRO2A, anticorps Dm5HTdro2A, anticorps Dmel\\CG16720, anticorps d5-HT1A, anticorps 5htr1a, anticorps htr1a, anticorps HTR1A, anticorps Htr1a, anticorps 5-Ht1a, anticorps Gpcr18, anticorps 5-HT-1A, anticorps 5-HT1A, anticorps 5HT1a, anticorps ADRB2RL1, anticorps ADRBRL1, anticorps G-21, anticorps PFMCD, anticorps RAT5HT1A, anticorps 5ht1a, anticorps adrb2rl1, anticorps adrbrl1, anticorps htr1a-A, anticorps 5-hydroxytryptamine (serotonin) receptor 1A, anticorps 5-hydroxytryptamine receptor 1A, anticorps 5-hydroxytryptamine (serotonin) receptor 1A a, anticorps 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog, anticorps 5-HT1A, anticorps HTR1A, anticorps htr1aa, anticorps Htr1a, anticorps htr1a.L

Sujet: HTR1A(5-HYDROXYTRYPTAMINE RECEPTOR 1A), also called SEROTONIN 5-HT-1A RECEPTOR or BETA-2-ADRENERGIC RECEPTOR-LIKE PROTEIN G-21, is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin. It is a G protein-coupled receptor(GPCR) that is coupled to Gi/Go and mediates inhibitory neurotransmission. HTR1A denotes the human gene encoding for the receptor.The HTR1A gene is located at 5q12.3. The decreases in 5-HT-1A receptor densities correlated with decreased glucose utilization as measured by PET scan. Activation of 5-HT-1A receptors has been demonstrated to impair cognition, learning, and memory by inhibiting the release of glutamate and acetylcholine in various areas of the brain. 5-HT-1A receptors in the dorsal raphe nucleus are co-localized with neurokinin 1(NK1) receptors and have been shown to inhibit the release of substance P, their endogenous ligand.

Synonyms: 5 HT 1A antibody|5 HT receptor 1A antibody|5 HT1A antibody|5 HT1A receptor antibody|5 hydroxytryptamine(serotonin) receptor 1A antibody|5 hydroxytryptamine(serotonin) receptor 1A G protein coupled antibody|5 hydroxytryptamine receptor 1A antibody|5-HT-1A antibody|5-HT1A antibody|5-hydroxytryptamine receptor 1A antibody|5HT 1A antibody|5HT 1A receptor antibody|5HT receptor 1A antibody|5HT1a antibody|5HT1A_HUMAN antibody|ADRB2RL1 antibody|ADRBRL1 antibody|G 21 antibody|G protein coupled receptor antibody|G-21 antibody|Gpcr 18 antibody|Gpcr18 antibody|Guanine nucleotide binding regulatory protein-coupled receptor antibody|HTR1A antibody|PFMCD antibody|Serotonin 1A receptor antibody|Serotonin 5HT1A receptor antibody|Serotonin receptor 1A antibody

UniProt: P08908

Pathways: Signalistation JAK/STAT, Synaptic Membrane, Feeding Behaviour