MAPK14 anticorps (pThr180, pTyr182)

N° du produit ABIN319104

Détail du produit anti-MAPK14 anticorps

Antigène: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Épitope: pThr180, pTyr182

Reactivité: Humain, Souris, Rat, Chien, Poulet, Boeuf (Vache), Singe, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK14 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody is specific for p38 mitogen-activated protein kinase (p38 MAPK), also known as MAPK14, when phosphorylated at Threonine 180 and Tyrosine 182.

Réactivité croisée (Details): Species reactivity (expected):Chicken, Zebrafish, Bovine, Monkey, Mouse and Canine (Dog).
Species reactivity (tested):Human and Rat.

Purification: Affinity Chromatography.

Immunogène: Synthetic phosphopeptide corresponding to an amino acid sequence within p38 MAPK which includes phosphorylated Thr180 and Tyr182.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/1000. This p38 MAPK antibody Recognises a band of approximately 39 kD in Western blots ofanisomycin C-6 glioma cell lysates. For the detection of phosphoproteins, Threonine and Tyrosine phosphatase inhibitors suchas 10 mM Sodium Fluoride and 1 mM Sodium Orthovanadate should be added to the samplebuffer. Milk or other casein-based blocking solutions are not recommended as casein is aphosphoprotein and its use can result in high background.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % BSA and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MAPK14

Antigène: MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

Autre désignation: MAP Kinase p38 alpha / MAPK14 (MAPK14 Produits)

Synonymes: anticorps CSBP, anticorps CSBP1, anticorps CSBP2, anticorps CSPB1, anticorps EXIP, anticorps Mxi2, anticorps PRKM14, anticorps PRKM15, anticorps RK, anticorps SAPK2A, anticorps p38, anticorps p38ALPHA, anticorps CRK1, anticorps Csbp1, anticorps Csbp2, anticorps Exip, anticorps Hog, anticorps Prkm14, anticorps Prkm15, anticorps Sapk2A, anticorps p38Hog, anticorps p38alpha, anticorps p38b, anticorps zp38b, anticorps MAPK14, anticorps 186F5S, anticorps BG:DS00797.3, anticorps CG7393, anticorps D-p38, anticorps D-p38 MAPK, anticorps D-p38b, anticorps Dm p38b, anticorps Dmel\\CG7393, anticorps Dmp38b, anticorps Dp38, anticorps Dp38b, anticorps ESTS:186F5S, anticorps Mpk34C, anticorps anon-sts23, anticorps dp38b, anticorps p38 MAPK, anticorps p38 beta, anticorps p38B, anticorps p38Kb, anticorps p38beta, anticorps Crk1, anticorps p38-alpha, anticorps p38MAPK, anticorps p38a, anticorps csbp, anticorps mapk14a, anticorps mxi2, anticorps sapk2, anticorps sapk2a, anticorps AP22.98, anticorps AP22_98, anticorps ATMPK14, anticorps mitogen-activated protein kinase 14, anticorps SAPK2a, anticorps MAP kinase 14A, anticorps MAP kinase p38a, anticorps MAPK 14A, anticorps fk28c03, anticorps hm:zeh1243, anticorps wu:fk28c03, anticorps zp38a, anticorps P38C-CRK, anticorps mitogen-activated protein kinase 14, anticorps mitogen activated protein kinase 14, anticorps mitogen-activated protein kinase 14b, anticorps p38b MAP kinase, anticorps mitogen-activated protein kinase 14 S homeolog, anticorps mitogen-activated protein kinase 14a, anticorps CRK proto-oncogene, adaptor protein, anticorps MAPK14, anticorps Mapk14, anticorps mapk14b, anticorps p38b, anticorps mapk14.S, anticorps MPK14, anticorps mapk14a, anticorps CRK

Sujet: P38 MAPK is a serine/threonine kinase which plays an important role in signal transduction, contributing to the regulation of many cellular processes including cell differentiation and inflammation. The protein is activated by phosphorylation of threonine 180 and tyrosine 182, by several upstream kinases, in response to a wide range of extracellular stimuli such as UV B irradiation or endotoxin exposure.Synonyms: CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, MAX-interacting protein 2, MXI2, Mitogen-activated protein kinase 14, SAPK2A, p38 alpha

ID gène: 1432

NCBI Accession: NP_001306

UniProt: Q16539

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins