BMPR2
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Antigène
BMPR2
(Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
anticorps BMPR-II, anticorps BMPR3, anticorps BMR2, anticorps BRK-3, anticorps PPH1, anticorps T-ALK, anticorps 2610024H22Rik, anticorps AL117858, anticorps AW546137, anticorps BB189135, anticorps BMP-2, anticorps BMPR-2, anticorps BMPRII, anticorps Gm20272, anticorps Bmpr-II, anticorps bmprii, anticorps bone morphogenetic protein receptor type 2, anticorps bone morphogenetic protein receptor, type II b (serine/threonine kinase), anticorps bone morphogenetic protein receptor, type II (serine/threonine kinase), anticorps BMPR2, anticorps bmpr2b, anticorps Bmpr2
Sujet
BMPR2 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in BMPR2 have been associated with primary pulmonary hypertension.Synonyms: BMP type II receptor, BMPR-II, Bone morphogenetic protein receptor type II, Bone morphogenetic protein receptor type-2, PPH1