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CD28 anticorps

CD28 Reactivité: Souris FACS, IP, Func Hôte: Hamster Monoclonal PV-1 unconjugated

N° du produit ABIN370909

Fiche de données

Antigène Voir toutes CD28 Anticorps

CD28
Reactivité
182

130

60

38

21

20

12

12

7

7

6

5

2

1

1

1

1

1
Souris
Hôte
143

78

29

18

8

3

2

1
Hamster
Clonalité
202

74

3
Monoclonal
Conjugué
95

30

28

20

15

7

7

6

6

5

4

4

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Cet anticorp CD28 est non-conjugé
Application
206

95

51

49

40

30

30

26

21

17

13

7

7

6

6

5

4

4

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Attributs du produit

Synonyms: TP44, T-cell-specific surface glycoprotein CD28

Purification

Purified

Clone

PV-1

Isotype

IgG

Top Product

Discover our top product CD28 Anticorps primaire
anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reactivité: Humain, Souris, Rat FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Hôte: Lapin Polyclonal unconjugated

anti-CD28 (CD28) antibody
CD28 Reactivité: Humain, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Hôte: Souris Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) antibody (FITC)
CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 FITC

anti-CD28 (CD28) (AA 19-152) antibody
CD28 Reactivité: Humain FACS, ELISA Hôte: Lapin Monoclonal DM61 unconjugated Recombinant Antibody

anti-CD28 (CD28) antibody
CD28 Reactivité: Humain, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Hôte: Souris Monoclonal CD28-2 unconjugated

anti-CD28 (CD28) antibody
CD28 Reactivité: Rat FACS, IP Hôte: Souris Monoclonal JJ319 unconjugated

anti-CD28 (CD28) antibody (PE)
CD28 Reactivité: Rat FACS Hôte: Souris Monoclonal JJ319 PE

anti-CD28 (CD28) antibody (APC)
CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 APC

anti-CD28 (CD28) antibody (PE)
CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 PE

anti-CD28 (CD28) antibody (PerCP)
CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 PerCP

Indications d'application

Flow Cytometry. (Ref.8-10)Immunoprecipitation. (Ref.8)Functional Assay: In vitro costimulation of T cells and NK cells. (Ref.8,9)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Concentration

0.5 mg/mL

Buffer

100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Stock

4 °C/-20 °C

Stockage commentaire

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption

12 months
Antigène

CD28

Autre désignation

CD28 (CD28 Produits)

Synonymes

anticorps Tp44, anticorps CD28RNA, anticorps cd28, anticorps CD28 molecule, anticorps CD28 antigen, anticorps Cd28 molecule, anticorps CD28 molecule L homeolog, anticorps CD28, anticorps Cd28, anticorps cd28.L

Sujet

CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. (Ref.1-4) CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. (Ref.5) CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses. (Ref.6-9)Synonyms: T-cell-specific surface glycoprotein CD28, TP44

UniProt

P31041

Pathways

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response