APH1A anticorps (Internal Region)

N° du produit ABIN374764

Détail du produit anti-APH1A anticorps

Antigène: APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp APH1A est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to APH1A.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-HVTDRSDARLQYG, from the internal region of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/128000. Western Blot: 0.05 - 0.1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur APH1A

Antigène: APH1A (Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))

Autre désignation: APH1A (APH1A Produits)

Synonymes: anticorps 6530402N02Rik, anticorps APH-1, anticorps APH-1A, anticorps CGI-78, anticorps RGD1311546, anticorps APH-1a, anticorps aph-1 homolog A, gamma-secretase subunit, anticorps aph-1 homolog A, gamma secretase subunit L homeolog, anticorps aph-1 homolog A, gamma secretase subunit, anticorps anterior pharynx defective 1 homolog A (C. elegans), anticorps aph1 homolog A, gamma secretase subunit, anticorps acylamino-acid-releasing enzyme-like, anticorps APH1A, anticorps aph1a.L, anticorps Aph1a, anticorps LOC100219182

Sujet: Anterior Pharynx Defective 1 (APH1a) is an integral transmembrane protein forming a component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. The gamma-secretase complex is an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein).Synonyms: APH-1A, Aph-1 alpha, CGI-78, Gamma-secretase subunit APH-1A, PSF, Presenilin-stabilization factor

ID gène: 51107, 9606

UniProt: Q96BI3

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway