c-MET anticorps (pTyr1234, pTyr1235)
Aperçu rapide pour c-MET anticorps (pTyr1234, pTyr1235) (ABIN387740)
Antigène
Voir toutes c-MET (MET) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- pTyr1234, pTyr1235
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Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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Immunogène
- This monoclonal antibody is generated from mice immunized with a KLH conjugated synthetic peptide corresponding to sequences in Tyr1234/1235 region of human Met and residues both Tyr1234 and Tyr1235 are phosphorylated.
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Isotype
- IgG1
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Indications d'application
- WB: 1:100~500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- c-MET (MET) (Met Proto-Oncogene (MET))
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Autre désignation
- MET/HGFR
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Sujet
- The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
- 155541
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ID gène
- 4233
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NCBI Accession
- NP_000236, NP_001120972
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UniProt
- P08581
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Pathways
- Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
Antigène
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