CDK7 anticorps (C-Term)

N° du produit ABIN452138

Détail du produit anti-CDK7 anticorps

Antigène: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Épitope: C-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDK7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Specificité: Mo-1.1 recognizes the key cell cycle regulator cdk7, which is essential to activate the cdk2 kinase in G1 phase and the cdc2 kinase in G2/M phase.

Attributs du produit: Synonyms: CAK1, P39 Mo15, STK1, CDK-activating kinase, Cell division protein kinase 7, TFIIH basaltranscription factor complex kinase subunit, 39 kDa protein kinase

Purification: Protein A affinity chromatography

Immunogène: Recombinant C-terminal 221 aa fragment of human wild-type cdk7/CAK (cyclin activatingkinase)

Clone: MO-1-1

Isotype: IgG2b

Information d'application

Indications d'application: Immunohistochemistry of frozen sections: 1/10 - 1/20, 1h at RT. Immunofluorescence. Immunoprecipitation of active kinase complex. Cell sorting (FACS analysis). Immunoblotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in 1 mL dist. water (final solution contains 0.09 % NaN3, 0.5 % BSA in PBS buffer, pH 7.4).

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CDK7

Antigène: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Autre désignation: CDK7 (CDK7 Produits)

Synonymes: anticorps CAK1, anticorps CDKN7, anticorps HCAK, anticorps MO15, anticorps STK1, anticorps p39MO15, anticorps AI323415, anticorps AI528512, anticorps C230069N13, anticorps Cdkn7, anticorps Crk4, anticorps CD 7, anticorps CDK7, anticorps CG3319, anticorps DmCDK7, anticorps DmCdk7, anticorps DmMO15, anticorps DmMo15, anticorps Dmcdk7, anticorps Dmel\\CG3319, anticorps Mo15, anticorps cdk-7, anticorps cdk7, anticorps dCdk7, anticorps p40[MO15], anticorps p40MO15, anticorps stk1, anticorps zgc:85821, anticorps cak1, anticorps cdkn7, anticorps p39mo15, anticorps cyclin dependent kinase 7, anticorps cyclin-dependent kinase 7, anticorps Cyclin-dependent kinase 7, anticorps cyclin-dependent kinase 7 L homeolog, anticorps CDK7, anticorps Cdk7, anticorps cdk7.L, anticorps cdk7

Sujet: Cdk7 is a member of the cyclin dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. Cdk7 forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.Synonyms: 39 kDa protein kinase, CAK1, CDK-activating kinase, Cell division protein kinase 7, P39 Mo15, STK1, TFIIH basal transcription factor complex kinase subunit

ID gène: 1022

UniProt: P50613

Pathways: Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase