HLA-DRB1 anticorps (N-Term)

N° du produit ABIN453100

Détail du produit anti-HLA-DRB1 anticorps

Antigène: HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-DRB1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide selected from the N-terminal region of human HLA-DRB1

Information d'application

Indications d'application: Western blot: 1: 100 - 1: 500. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur HLA-DRB1

Antigène: HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1 (HLA-DRB1))

Autre désignation: HLA Class II DR beta 1 / HLA-DRB1 (HLA-DRB1 Produits)

Synonymes: anticorps MGC108235, anticorps DRB1, anticorps DRw10, anticorps HLA-DR1B, anticorps HLA-DRB, anticorps SS1, anticorps major histocompatibility complex, class II, DR beta 1, anticorps hla-drb1, anticorps HLA-DRB1

Sujet: HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons.Synonyms: DR-1, DR1, DRB1-1 beta chain, HLA class II histocompatibility antigen, MHC class II antigen DRB1

Poids moléculaire: 29914 Da

ID gène: 9606

UniProt: P04229

Pathways: TCR Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Cancer Immune Checkpoints