KLRC1
Reactivité: Souris
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Antigène
KLRC1
(Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
anticorps rNKG2A, anticorps NKG2-A, anticorps NKG2A, anticorps KLRC1, anticorps CD159A, anticorps NKG2, anticorps CD159a, anticorps NKG2B, anticorps killer cell lectin like receptor C1, anticorps NKG2-A/NKG2-B type II integral membrane protein-like, anticorps killer cell lectin-like receptor subfamily C, member 3, anticorps killer cell lectin-like receptor subfamily C, member 1, anticorps Klrc1, anticorps KLRC1, anticorps NKG2A, anticorps KLRC3
Sujet
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. This protein belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.Synonyms: CD159 antigen-like family member A, CD159a, KLRC1, NK cell receptor A, NKG2-A/B-activating NK receptor, NKG2-A/NKG2-B type II integral membrane protein, NKG2A