CLEC4E
Reactivité: Humain, Rat
WB, ELISA, IHC (p), IHC (fro)
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
ELISA. Western blot (1: 250 - 1: 1000). Immunofluorescence (1: 250 - 1: 500). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Date de péremption
12 months
Antigène
CLEC4E
(C-Type Lectin Domain Family 4, Member E (CLEC4E))
anticorps CLECSF9, anticorps MINCLE, anticorps C86253, anticorps Clecsf9, anticorps Mincle, anticorps CLEC4E, anticorps C-type lectin domain family 4 member E, anticorps C-type lectin domain family 4, member e, anticorps C-type lectin domain family 4, member E, anticorps CLEC4E, anticorps Clec4e, anticorps LOC611538
Sujet
MINCLE (macrophage inducible C-type lectin, also called CLEC4E or CLECSF9), which is a diverse family of protein which was originally defined by their ability to recognize a wide range of ligand of carbohydrate structure. MINCLE expressed in macrophages subjected to several types of stress. It plays an essential role in response to trehalose-6,6'-dimycolate (TDM) and activated by a synthetic analogue, trehalose dibehenate (TDB). Recently it was reported that MINCLE is associated with an immunoreceptor tyrosine-based activation motif-containing Fc receptor γ chain (FcRγ) and functions as an activating receptor for damaged self- and non-self-pathogenic fungi.Synonyms: C-type lectin domain family 4 member E, C-type lectin superfamily member 9, CLECSF9, MINCLE, Macrophage-inducible C-type lectin