NLRP3 anticorps (AA 81-93)
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- Antigène Voir toutes NLRP3 Anticorps
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
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Épitope
- AA 81-93
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Reactivité
- Humain, Singe
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NLRP3 est non-conjugé
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Application
- ELISA
- Specificité
- Human NLRP3. This antibody is expected to recognize all reported isoforms (NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1). Reported variants NP_001073289.1 and NP_004886.3 represent identical protein.
- Homologie
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Panda, Bat, Pig (92%) Dog, Bovine, Rabbit (85%).
- Purification
- Immunoaffinity purified
- Immunogène
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Synthetic peptide RDLYEKAKRDEPK-C from the N-terminus (near) of human NLRP3 (NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Panda, Bat, Pig (92%), Dog, Bovine, Rabbit (85%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product NLRP3 Anticorps primaire
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- Indications d'application
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Approved: Peptide-ELISA (1:32000)
Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave an approx 36 kDa band in Human Peripheral Blood Mononucleocytes lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the smallest calculated size of 106 kDa according to NP_899632.1. The 36 kDa band was successfully blocked by incubation with the immunizing peptide. - Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Minimize freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze-thaw cycles.
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- Antigène
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
- Autre désignation
- NALP3 / NLRP3 (NLRP3 Produits)
- Synonymes
- anticorps CIAS1, anticorps Nalp3, anticorps avp, anticorps cias1, anticorps nalp3, anticorps pypaf1, anticorps agtavprl, anticorps AGTAVPRL, anticorps AII, anticorps AVP, anticorps C1orf7, anticorps CLR1.1, anticorps FCAS, anticorps FCU, anticorps MWS, anticorps NALP3, anticorps PYPAF1, anticorps AII/AVP, anticorps Cias1, anticorps Mmig1, anticorps Pypaf1, anticorps NLR family pyrin domain containing-like, anticorps NLR family pyrin domain containing 3, anticorps NLR family, pyrin domain containing 3 L homeolog, anticorps NLR family, pyrin domain containing 3, anticorps NLRPL, anticorps NLRP3, anticorps nlrp3.L, anticorps Nlrp3
- Sujet
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Name/Gene ID: NLRP3
Synonyms: NLRP3, AGTAVPRL, AII, C1orf7, Caterpiller protein 1.1, Cryopyrin, FCAS, FCU, PYPAF1, NALP3, CIAS1, CLR1.1, MWS - ID gène
- 114548
- NCBI Accession
- NP_004886, NP_899632, NP_001120933, NP_001120934
- UniProt
- Q96P20
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
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