RAP1A anticorps

N° du produit ABIN4952368

Détail du produit anti-RAP1A anticorps

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAP1A est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Amino acids EIFYDLVRQINRKTPVEKKKPKKKSC of human Ras-related protein Rap-1A were used as the immunogen for the RAP1A antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RAP1A antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the RAP1A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur RAP1A

Antigène: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Autre désignation: RAP1A / KREV1 (RAP1A Produits)

Synonymes: anticorps KREV-1, anticorps KREV1, anticorps RAP1, anticorps SMGP21, anticorps AI848598, anticorps G-22K, anticorps Krev-1, anticorps Rap1, anticorps RAP-1A, anticorps rap 1A, anticorps wu:fc66g06, anticorps zgc:86676, anticorps krev-1, anticorps krev1, anticorps rap1, anticorps RAP1A, member of RAS oncogene family, anticorps RAS-related protein 1a, anticorps RAP1A, member of RAS oncogene family a, anticorps RAP1A, member of RAS oncogene family L homeolog, anticorps RAP1A, anticorps Rap1a, anticorps rap1aa, anticorps rap1a.L

Sujet: Ras-related protein Rap-1A is a protein that in humans is encoded by the RAP1A gene. This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. And it is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. Additionally, the encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

UniProt: P62834

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor