c-MET anticorps (Catalytic Domain)
Aperçu rapide pour c-MET anticorps (Catalytic Domain) (ABIN3031757)
Antigène
Voir toutes c-MET (MET) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Catalytic Domain
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Fonction
- MET Antibody (HGFR)
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Purification
- Purified
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Immunogène
- This MET antibody was produced from mice immunized with purified recombinant protein encoding the catalytic domain of human MET/HGFR.
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Isotype
- IgG1
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Indications d'application
- Titration of the MET antibody (HGFR) may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the MET antibody (HGFR) and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- c-MET (MET) (Met Proto-Oncogene (MET))
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Autre désignation
- MET
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Sujet
- The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- P08581
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Pathways
- Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
Antigène
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