PIK3CA anticorps (AA 504-533)
Aperçu rapide pour PIK3CA anticorps (AA 504-533) (ABIN3028924)
Antigène
Voir toutes PIK3CA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 504-533
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Purification
- Purified
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Immunogène
- A portion of amino acids 504-533 from the human protein was used as the immunogen for this PI3KCA antibody.
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Isotype
- Ig Fraction
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Indications d'application
- Titration of the PI3KCA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the PI3KCA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
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Autre désignation
- PI3KCA
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Sujet
- Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
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UniProt
- P42336
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Pathways
- Signalisation PI3K-Akt, Signalisation RTK, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling
Antigène
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