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NFKBIA anticorps (pTyr42)
NFKBIA
Reactivité: Humain, Souris, Rat
IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-NFKBIA anticorps
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Antigène
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NFKBIA
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
Épitope
Tous les épitopes à travers NFKBIA Anticorps.
pTyr42
Reactivité
Toutes les réactivités sur NFKBIA Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur NFKBIA Anticorps
Lapin
Clonalité
Toutes les clonalités sur NFKBIA Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers NFKBIA Anticorps
Cet anticorp NFKBIA est non-conjugé
Application
Tous les applications à travers NFKBIA Anticorps.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
This antibody detects endogenous levels of IkappaB-alpha protein only when phosphorylated at Tyr42.
Réactivité croisée (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography
Pureté
> 95 % by SDS-PAGE
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Alternatives
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anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA) (AA 1-120) antibody
NFKBIA
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet
WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Information d'application
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Indications d'application
Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur NFKBIA
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Antigène
NFKBIA
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
Autre désignation
NFKBIA / IKBA (NFKBIA Produits )
Synonymes
anticorps IKBA, anticorps MAD-3, anticorps NFKBI, anticorps AI462015, anticorps Nfkbi, anticorps RL/IF-1, anticorps ECI-6/IKBA, anticorps NFKBIA, anticorps ikbaB, anticorps wu:fb81f08, anticorps zgc:56666, anticorps zgc:77616, anticorps ikbaA, anticorps wu:fj16a07, anticorps zgc:85769, anticorps NFKB inhibitor alpha, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a, anticorps NFKBIA, anticorps Nfkbia, anticorps nfkbiab, anticorps nfkbiaa
Sujet
On the basis of both functional and structural considerations, members of the IkappaB family of proteins can be divided into four groups. The first of these groups, IkappaB-alpha (a 35-37 kDa protein), includes the avian protein pp40 and the mammalian MAD-3, both of which inhibit binding of p50-p65 NFkappaB complex or Rel protein to their cognate binding sites but do not inhibit the binding of p50 homodimer to kappaB sites, suggesting that the IkappaB-alpha family binds to the p65 subunit of p50-p65 heterocomplex through ankyrin repeats. The second member of the IkappaB family is represented by a 45 kDa protein designated IkappaB-beta. The third group of IkappaB proteins is represented by IkappaB-gamma, a 70 kDa protein identical in sequence with the Cterminal domain of the p110 precursor of NFkappaB p50 and expressed predominantly in lymphoid cells.Synonyms: I kappa B-alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappa-B inhibitor alpha, NFKBI
Poids moléculaire
approx. 36 kDa
ID gène
4792
NCBI Accession
NP_065390
UniProt
P25963
Pathways
Signalisation NF-kappaB , TCR Signaling , Signalisation TLR , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Maintenance of Protein Location , Hepatitis C , Protein targeting to Nucleus , Toll-Like Receptors Cascades , BCR Signaling
Vus récemment
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